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Improved handling of dysfunctional labour confirmed by article in PLOS ONE

By October 26, 2016 April 2nd, 2020 No Comments

An article published in PLOS ONE (published online 26 October, 2016, doi: 10.1371/journal.pone.0161546) concludes that measuring lactate in amniotic fluid (AFL) is a good predictor of delivery outcome in arrested deliveries. Low levels of AFL may support the decision to continue a prolonged vaginal labour by augmentation with oxytocin. A high level of AFL correlates with operative interventions and post-partum complications.

​The study was performed in four different countries (France, Sweden, Switzerland and Tanzania) and included 3000 delivering women. In the study, primiparous women all with a singleton pregnancy, gestational age 37 to 42 weeks and no maternal /fetal chronic and/or pregnancy-related conditions were included. A spontaneous onset of labour, regular contractions and cervical dilation ≥ 3 cm was also required.

​AFL was measured using a point of care device (LMU061) from ObsteCare. The only device on the market that is regulatory approved for measuring lactate in amniotic fluid during labour. The study was part-financed by the Bill and Melinda Gates Foundation.

​These findings confirm earlier findings that AFL can be used as a good bedside tool when treating women suffering from a dysfunctional delivery. By using AFL monitoring in combination with Oxytocin infusion, the frequency of operative deliveries can be reduced and delivery times be optimized.